Cellular Rejuvenation
Translating senescence insights into tissue-level recovery and functional restoration strategies.
Approach: Combine selective senescent-cell clearance with context-aware cell model validation, including 3D systems and translational endpoints.
Program Priorities
- Testing candidate molecules across multiple senescent cell types.
- Comparing cell-state recovery signals after compound treatment.
- Selecting leads with strong efficacy-safety balance for next stages.
Why It Matters
Rejuvenation outcomes are critical for demonstrating practical healthspan impact beyond purely mechanistic molecular readouts.